CD4+ Regulatory T (Treg) cells suppress excessive immune responses thus maintain sanity in the host immune system. Cancer cells take advantage of the immune-suppressive features of CD4+ Tregs to dampen antitumor immune responses. Though the immunosuppressive role of Tregs is critical in malignant transformations, what’s not known is the mechanism of how CD4+ Tregs achieve… Continue reading Tregs in the tumor microenvironment: A friend or a foe?