In the past, cancer was considered a single disease characterized by the uncontrolled growth of cells. However, the advancement in genetics and proteomics in recent times has revealed that cancer is a combination of various diseases. Nevertheless, cancers share several common features which are wonderfully described by Hanahan and Weinberg in their review “Hallmarks of… Continue reading Not Single Anymore – Fighting Breast Cancer with Triple Drug Combination
Blog
Revival of cytostatic drugs as cancer therapy
In the absence of functional apoptotic pathway, most chemotherapy and probably many other anticancer drugs suppress tumor via senescence. However, induction of senescence isn’t considered a good therapeutic outcome and many researchers are looking to combine cytostatic drugs, with other drugs which would selectively kill the senescent cells (senolytics). In a recent paper published in… Continue reading Revival of cytostatic drugs as cancer therapy
Turning on the self-destruct switch
Cells have evolved with an inbuilt self-destruction switch called apoptosis. The ability of cells to commit suicide helps us stay disease-free by removing damaged and worn-out cells. Cancer researchers are particularly interested in understanding this phenomenon in order to use it against cancer cells. In December 2018, 3 research articles were published in the same… Continue reading Turning on the self-destruct switch